Dr Caroline Dewar

Lecturer in Parasitology

Research Overview

My laboratory investigates the fundamental cellular mechanisms involved in maintaining mitochondrial function. Mitochondria are hubs for energy generation, metabolic and cell death pathways, thus guarding over the critical balance between cellular survival and death. Mitochondrial dysfunction has a central role in neurodegenerative and cardiovascular disorders, cancers and metabolic diseases.

Our research is focussed on understanding the pathways which counteract mitochondrial dysfunction in African trypanosomes, devastating parasites of both humans and cattle in sub-Saharan Africa. By studying these fascinating evolutionarily-diverged eukaryotes, we can shed light on the underlying features of mitochondrial quality control pathways, while also informing parasite drug discovery.


Publication peer-review


Participation in workshop, seminar, course


Symposium


Visiting an external academic institution


Participation in workshop, seminar, course


Participation in workshop, seminar, course


Other


Editorial activity


Types of Public engagement and outreach - Festival/Exhibition


Participation in workshop, seminar, course


Participation in workshop, seminar, course


Participation in conference - Academic


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Publication peer-review

  • Microbes, Pathogens and Immunity